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Tirzepatide was administered at a dose assumed to be below the lowest clinically applicable dose of 5 mg, based on C max [46], and the same dose was used for retatrutide

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The dephospho-CoA kinase (DPCK) domain of COASY catalyzes the final step in CoA synthesis by adding the phosphate from ATP to the 2-hydroxyl of the ribose from the adenine added in the previous reaction

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