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The peptide also appears to influence neurotransmitter systems, particularly the dopaminergic and GABAergic pathways, which may contribute to its observed effects on neurological function and behavior

The published clinical work in humans is mostly small, often industry-sponsored, and frequently confined to skin endpoints rather than hair-count endpoints

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The measurement precision available at the bottom of a titration schedule is considerably worse than the tolerance the trial itself enforced for its own analysis