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In preclinical studies published in Endocrinology, researchers found that chronic administration of AOD-9604 reduced body weight and body fat in obese mice while increasing beta-3 adrenergic receptor expression to levels comparable with lean mice
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
People may have low B12 levels if they are on a vegetarian or vegan diet
Its targeted mechanism of action makes it a valuable compound for investigating how NNMT inhibition influences metabolic health, mitochondrial function, and longevity-associated biological processes
Interestingly, the status of those in the younger age 26-49yrs group presented similar readings to those over 65 years of age
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