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10.2147/TCRM.S67076 34

in the hyperlipidemia group, rats were fed on a high-fat diet composed of 56.9% basic diet, 13% lard, 2% sesame oil, 20% refined sugar, 3% cholesterol, 0.1% sodium cholate and 5% peanuts for 16 weeks and were given saline (ip) for the final 4 weeks during 16-week high-fat diet treatment

4.3 Modulation of inflammatory status by tirzepatide Beyond metabolic regulation, obesity-related OSAS is closely linked to chronic low-grade systemic inflammation driven by intermittent hypoxia

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identified impaired leukemia inhibitory factor/signal transduction (LIF/STAT3) pathway and disrupted endoplasmic reticulum stress in mice treated with excessive P4, leading to potential inhibition of embryo implantation and uterine transformation (Liang et al., 2018)