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Minireview: tipping the balance: ligand-independent activation of steroid receptors

While most often associated with the vagina, it can happen on or in other areas of the body including the mouth and skin

Some individual trials and reports have similarly noted improved mood or reduced depressive symptoms in diabetic patients treated with GLP-1 RAs, potentially as a result of better overall health and possible direct neurochemical effects

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doi:10.1016/s0196-0709(00)80003-4