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Exposure to chemicals and other pollutants can increase the demand for the bodys antioxidants, while autoimmune diseases have also been shown to deplete glutathione

Associations among glutathione S-transferase T1, M1, and P1 polymorphisms and the risk of oral leukoplakia

This mechanistic insight led to the discovery of the GSH precursor N -acetylcysteine (NAC) as an effective antidote against APAP toxicity in mice and in patients [10, 11]

The compound DCZ0801 is a combination of pterostilbene and osalmide that was shown to reduce MM proliferation through the inhibition of glycolysis (Traversi et al., 2017)

Lastly, we asked whether our rapamycin strategy would also enhance the in vivo efficacy of CAR T cells from LTR