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New antidiabetic and anti-obesity drugs
The GPX4 pathway influences DCs survival, and ferroptotic stress may compromise T-cell activation, affecting immune tolerance (91, 96)
88 STAT3 forms complexes with TOX, directly binding promoters of inhibitory receptors such as PD-1, TIM-3, and LAG-3, increasing chromatin accessibility and enforcing an exhausted phenotype
All the data are presented as the means SDs
10.1038/s41556-019-0305-6 20 ConradM.PrattD
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