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The closed conformation of the peptide-free GLP-1R compared to GCGR is quite divergent in the extracellular region and may be a consequence of sequence diversity, which is important for understanding the signalling pathway for different receptors within the class B family
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After centrifugation for 5 min at 20,000 g , tris(2-carboxyethyl)phosphine was added to a final concentration of 1 mM and samples were incubated for 20 min
La absorcin muscular es entonces significativamente menor
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