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C.StrassburgerK.NowotnyB.KolbH.NowotnyP.BurkartV.et al (2015)
Difen Injection Product introduction Difen Injection is a pain-relieving medicine
During the dose-escalation period used in clinical trials and expected in clinical practice, each dose level reaches its own steady state before the next escalation step, ensuring that the pharmacokinetic transition between doses is gradual and predictable
Always inspect the injection for any particulate matter or discolouration before use
After 3-5 days, increase to 0.5 mg if tolerated
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