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doi: 10.1007/s00253-024-13367-0 22 KoshiD.UeshimaH.KawauchiM.NakazawaT.SakamotoM.HirataM.et al
What is new is the growing pile of evidence suggesting that activating those receptors, even at very low doses, can quiet the overactive immune response that defines conditions like rheumatoid arthritis , psoriasis, Hashimoto thyroiditis, and inflammatory bowel disease
We also see generalised hyperpigmentation which can be seen in extensive areas of the body, often where there are folds of skin, such as the armpits, or where there is increased sun exposure, such as the shoulders, as well as the intimate areas
The other complexes containing ethylenediamine, acetylacetonate, or 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane were inactive in cytotoxicity assays and proapoptotic and antimetastatic behaviour
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