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Ex-4 significantly reduces neuroinflammation by converting proinflammatory M1 microglia into anti-inflammatory M2 microglia both in vitro and in vivo through the rescue of the expression of Arf and Rho GAP adapter protein 3 (ARAP3)

Semaglutide is engineered to last much longer, allowing for sustained activity and more stable metabolic effects

This suggests that semaglutide could be a promising treatment option for individuals with both conditions

When oestrogen declines at menopause, the body defaults to storing fat centrally, around the abdomen and organs

It tells the pancreas to do that only when your blood glucose levels are elevated, Trujillo explains