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However, individuals who have type 2 diabetes alongside a need to minimise weight gain or promote weight loss may benefit from GLP-1/GIP therapy and its dual impact on type 2 diabetes management and weight loss
Glucoraphanin conversion into sulforaphane and related compounds by gut microbiota
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Johanson JF, Kralstein J
A 48-week Phase 2 trial reported in The Lancet in 2025 showed mean weight reduction ranging from approximately 9% at the lowest dose to 20% at the highest dose, compared with 0.4% on placebo
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