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Heart failure, kidney disease, high blood pressure, pregnancy, low-sodium diets, bleeding history, and medicine interactions require caution

The primary approach involves identifying and moderating intake of foods high in sulphur-containing compounds, which serve as substrates for bacterial production of hydrogen sulphide gas

10.1111/j.1463-1326.2010.01214.x 106 LimK

The SELECT trial, published in the New England Journal of Medicine in 2023, demonstrated that semaglutide significantly reduced major adverse cardiovascular events in patients with established cardiovascular disease and overweight or obesity, representing a landmark finding for GLP-1 receptor agonists in cardiovascular risk reduction