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Kraus D, Yang Q, Kong D, et al

SIRT1 activation promotes numerous anti-aging effects including enhanced mitochondrial biogenesis, improved stress resistance, reduced inflammation, and activation of cellular quality control mechanisms that remove damaged proteins and organelles

Published literature describes investigations into pathways such as angiogenesis, the nitric oxide (NO) system, and tissue repair signaling in rodent models (Sikiric et al., 2025, Pharmaceuticals)