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Gu J, Liu S, Mu N, Huang T, Zhang W, Zhao H, Shu Z, Zhang C, Hao Q, Li W, Xue X, Zhang W, Zhang Y (2017) A DPP-IV-resistant glucagon-like peptide-2 dimer with enhanced activity against radiation-induced intestinal injury
Jastreboff et al., NEJM, 2022 (SURMOUNT-1) The Next Generation of Metabolic Medicine The efficacy and safety of Tirzepatide are supported by the extensive SURPASS and SURMOUNT clinical trial programs, heralding a new era in weight management
It is engineered to resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), allowing for prolonged activity
Free Radic Biol Med 99:608622
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