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The best-supported benefits are weight reduction, BMI reduction, improved insulin resistance, and some improvements in androgen-related markers
Undigested food then stays in the stomach and can harden, often accompanied by symptoms such as nausea, vomiting, bloating, constipation, and abdominal discomfort
While oral formulations offer a new level of convenience, both oral Wegovy and orforglipron require once-daily dosing
Adding liraglutide to insulin therapy has also been seen to have significant reductions in HbA1c and weight loss, a 0.8% reduction of HbA1c and a mean weight loss of 5.1 kg, respectively
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