What clinicians are seeing over time is consistent with the early stages of treatment, with digestive symptoms remaining the most commonly reported
In the Phase 2 trial, fasting glucose increased transiently in some participants, more so at 8 mg and 12 mg, though GLP-1 and GIP co-activation appeared to offset most of this effect
Long-term metformin use can lower vitamin B12 levels in some people
This may involve oral or injectable forms of B12, depending on the individual's needs
Benefits Significant, clinically proven weight loss Reduced risk of Type 2 diabetes, high blood pressure, and cardiovascular disease Non-surgical, once-weekly injection Personalized dosing not a one-size-fits-all approach Physician-supervised by a board-certified plastic surgeon Built-in path to body contouring if needed after weight loss Best candidates for GLP-1 weight loss injections GLP-1 type medications are suitable for adults who: Have a body mass index (BMI) of 30 or higher (obesity) Have a BMI of 27 or higher (overweight) with at least one weight-related condition, such as type 2 diabetes, high blood pressure, or high cholesterol