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For context, tirzepatide (Mounjaro) is a dual GIP/GLP-1 receptor agonist, and semaglutide (Wegovy, Ozempic) is a GLP-1 receptor agonist
Tirzepatide produced approximately 22.5 percent at 72 weeks in SURMOUNT-1
One study found patients regained about two-thirds of their weight loss within a year after stopping weekly semaglutide injections
The liberated p53 then transcription-independently activates the pro-apoptotic protein BAX, thereby triggering the execution phase of apoptosis
