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Initial identification of the pore was done with the bottleneck radius parameter set to 1.2 with a tolerance of 3

Duttaroy 2021

Those papers which formed the preclinical rationale for dihexa's nootropic claims and for Athira's NIH grant applications had been cited as evidence that dihexa promoted synaptogenesis at rates far exceeding BDNF

Commercial products like Ozempic typically come as auto-injectors with preset doses, while compounded versions come in vials requiring manual dosing