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As a result, pyridoxine deficiency can lead to relevant neuropsychiatric manifestations, such as reduced neurotransmitter synthesis, depression, epilepsy, premature aging of neurons, paresthesias, cerebrovascular diseases, cognitive impairment and carpal tunnel syndrome (, , , , , ) In contrast, pyridoxine may have therapeutic potential for treating depression or aggressive behavior, since pyridoxine plays a crucial role in the tryptophan-serotonin pathway (, )
Only practical if your compounding pharmacy is local and the cost difference isn't prohibitive
Medical advice is also important before starting or changing vitamin B12 if a person has a diagnosed blood disorder, digestive disease, prior bowel or stomach surgery, or takes long-term medications that may affect B12 status
NPY is synthesized in both the peripheral and central nervous systems [168]
Dairy and Casein Cheese and milk are common culprits
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