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In October, at the American College of Rheumatology Convergence 2025, interim Phase 1b results for SBT777101, an autologous CAR regulatory T-cell therapy, showed early signs of clinical activity and a favorable safety profile with no dose-limiting toxicities, cytokine release syndrome or immune effector cell-associated neurotoxicity syndrome

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[9] In summary, while NAD+ Injection is a broadly applicable metabolic therapy, it should not be used by anyone allergic to it, and it is generally avoided in pregnant women, cancer patients, or those with serious chronic diseases, absent compelling medical rationale

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