GHRP-type peptides (ipamorelin, GHRP-6, GHRP-2, hexarelin) act on GHS-R1a, while GHRH analogs (CJC-1295, sermorelin, tesamorelin) act on GHRH-R
Though it is naturally produced in the body, ageing, poor diet, environmental pollutants, and stress can lower its levels, resulting in increased oxidative stress and hyperpigmentation
Ipamorelin activates the ghrelin/GHSR pathway to trigger physiologic GH release with minimal impact on other pituitary hormones, supporting protein synthesis, lean mass, recovery, and metabolic rate
The 30-day window is shorter than some competitors offer (Life Extension, for example, provides a full year), but it is generally enough time to identify any sensitivity or digestive issues
Ginkgo biloba EGb 761 at standardised therapeutic dosing for 12+ weeks showed benefit in a systematic review of eight trials (1,199 patients) [3]