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Principal research applications include: Comparative pharmacology of GLP-1R, GIPR, and GCGR individual and combined agonism In vitro receptor binding, selectivity, and signalling characterisation studies Preclinical metabolic modelling hepatic glucose output, adipose lipolysis, thermogenesis Beta-cell biology and pancreatic incretin responsiveness research Energy expenditure and brown adipose tissue activation under triple receptor engagement Mechanistic comparison with dual agonist classes (GLP-1R/GIPR