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Seventy percent of patients in the early- therapy subgroup no longer required insulin but none in the late-therapy group

Clinically tested (patch-tested for irritation)

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Sigma-1 receptor is a molecular target for novel neuroprotectant T-817MA

AP1 is a complex of several proteins including JUN, which is upregulated in motor neurons derived from SOD1 patients compared to other neurons, providing potential mechanistic insights into the selective degeneration of motor neurons in ALS (Bhinge et al., 2017)