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More recently, sodium-glucose cotransporter type 2 inhibitors have demonstrated to offer cardiovascular and renal protection, but the residual risk remains high and their antihyperglycemic efficacy is limited in moderate-severe CKD

The pharma is also running SYNCHRONIZE-CVOT, which will focus on overweight and obese patients with cardiovascular disease, chronic kidney disease or other risk factors for cardiovascular disease

On the other side, there are compounded versions of semaglutide and tirzepatide prepared by compounding pharmacies, often at a lower cost, and prescribed by a growing number of telehealth startups and clinics

Schlesinger, N., Yasothan, U

Formulators are shifting toward condition-specific blends that aid glycemic control, muscle preservation, and digestive balance