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stable up to 24 months

More importantly, when detailed cellular analyses were performed with electron microscopy (EM), exact same cellular problems were detected both in the UMNs of ALS patients with TDP-43 pathology and the CSMN of this mouse model of TDP-43 pathology 16

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In 1902 they discovered in anaesthetised dogs that a chemical messenger secreted by the intestinal lining into the bloodstream helped to stimulate the pancreas to produce digestive juices whenever food or acid was introduced into the duodenum