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Any combined schedule should be treated as community-reported practice, not a clinically proven protocol

Endogenous GLP-1 is typically degraded within minutes by the circulating enzyme dipeptidyl peptidase-4 (DPP-IV)

The result is a synergistic pulse that is significantly larger than either peptide alone, while still being a physiological pulse rather than a pharmacological spike

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Alongside its popularity, however, lawsuits have emerged alleging that Wegovy can cause severe gastrointestinal complications including bowel obstruction, ileus, and intestinal blockage, conditions that often require hospitalization or surgery