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We recommend that all hits should be resynthesised and purified to confirm activity but if this is not possible then compounds from commercial sources should be purified with metal scavenging technology before confirming activity

Hypomethylating Agent (HMA) Therapy and Venetoclax (VEN) with FLT3 Inhibitor Triplet Therapy Is Highly Active in Older/Unfit Patients with FLT3 Mutated AML

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However, as with any supplement, excessive use can lead to potential risks