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(6) Terry J Smith (2010) Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases

It loses its glow and turns out saggy, wrinkled, and pigmented

Marso SP et al

The drug is expected to seek FDA approval in 2025

To summarize, age-related changes in mitochondria, antioxidant gene expression, and epigenetic regulation progressively lead to redox imbalance in oocytes, compromising their metabolic competence and genomic integrity