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In pulmonary arterial hypertension (PAH), specific studies using monocrotaline (MCT)-induced PAH models suggest that liraglutide acts through the NO/sGC/cGMP pathway, increasing NO release, activating soluble guanylate cyclase (sGC), and enhancing cyclic guanosine monophosphate (cGMP) synthesis

non-osteoporosis) were compared using independent t-tests for continuous variables and chi-square tests for categorical variables

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What happens with extended use

For gastrointestinal indications, systemic or oral administration is appropriate because the entire gut is the target