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MACs apply Local Coverage Determinations (LCDs) and National Coverage Determinations (NCDs) to evaluate whether the submitted drug meets medical necessity standards

Ask about functional limitations (inability to play with their kids) and the psychological impacts of obesity as potential motivating factors for patients instead of solely focusing on the metabolic impacts of obesity

However, a third of high-dose patients experienced nausea while 24% experienced vomiting, compared with 10.4% and 3.5% respectively for the placebo group

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