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The knowledge inspired development of new therapeutic molecules that specifically bind FcRn to outcompete endogenous IgG

doi:10.1016/j.vetimm.2012.04.001

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Glutamine activates mTORC1 by enhancing glutaminolysis and the production of -KG, which is helpful for the GTP-loading of RagB and lysosomal translocation (Duran et al., 2012)