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Wong D, Dorovini-Zis K, Vincent SR
Authors: Thomas Kruse, Jakob Lerche Hansen, Kirsten Dahl, Lauge Schffer, Ulrich Sensfuss, Christian Poulsen, Morten Schlein, Ann Maria Kruse Hansen, Claus Bekker Jeppesen, Charlotta Dornonville de la Cour, Trine Ryberg Clausen, Eva Johansson, Simone Fulle, Rikke Bjerring Skyggebjerg, Kirsten Raun URL: This paper details the medicinal chemistry efforts that led to the design and synthesis of cagrilintide, a long-acting amylin analogue for the treatment of obesity
Introduction Under normal physiological conditions, only specific substances from the bloodstream are allowed to enter the brain parenchyma due to a highly specialized blood-brain barrier (BBB
Moreover, DTCM-g demonstrated radiosensitization capabilities in glioblastoma, 50,51 further emphasizing its potential as a valuable therapeutic drug in radiotherapy
DSIP works faster, with sleep pressure reported within hours, but even its full effects on sleep architecture normalization develop over multiple doses
