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10.2147/DDDT.S284163 79 XuC.SunL.RenF.HuangP.TianZ.CuiJ.et al (2020)
NHS approach to B12 deficiency: NICE Clinical Knowledge Summaries recommend investigating B12 deficiency in patients presenting with macrocytic anaemia, unexplained neurological symptoms, or risk factors including pernicious anaemia, gastrectomy, malabsorption disorders, metformin use, proton pump inhibitors, or nitrous oxide exposure
Although it entered phase 1 trials in consideration as a treatment of ulcerative colitis, it has not been approved by the US Food and Drug Administration (FDA) for medical use, and data on human subjects is lacking
High-purity material from a trusted supplier like Pure Tested Peptides removes one major variable from this equation, making it easier to determine whether differences come from methodology, biological variation, or genuine limitations of the compound itself
Mechanistic studies to better understand the molecular targets and pathways involved in peptide action could help identify potential adverse effects and inform safer clinical use
