In a drug safety update, published on 28 January 2025, the MHRA cited findings of a recent European Medicines Agency (EMA) review of the available evidence for all GLP-1 and dual GIP/GLP-1 RAs, which concluded that data supports an association between the medicines and the potential risk of pulmonary aspiration during anaesthesia or deep sedation, owing to the delayed gastric emptying linked to these medicines
Health Canada described the generic versions of semaglutide as complex synthetic products that are pharmaceutically equivalent to the brand name biologic drug, noting its review ensures that differences between these products do not affect the safety, efficacy, or quality of the drug
An overview of PROTACs: a promising drug discovery paradigm
Your gut produces most of the GLP-1 in your body The L-cells that produce GLP-1 live in your intestinal lining, with the highest concentrations in the ileum (the last section of your small intestine) and the colon
miRNA delivery by nanosystems: state of the art and perspectives