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Both the p33 and p55 subunits of the Helicobacter pylori VacA toxin are targeted to mammalian mitochondria

At this concentration, the maximum comfortable dose per vial is approximately 1.25 mg weekly, since higher doses would require nearly the full vial each week

If youre unfamiliar with that drug, marketed as Bydureon (exenatide) Pen by AstraZeneca, thats because it was discontinued in 2021 due to business reasons. Could it also have something to do with the next generation of GLP-1s being even better

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