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Neuropathol Appl Neurobiol 37(7):711726 Waki H, Liu B, Miyake M, Katahira K, Murphy D, Kasparov S et al (2007) Junctional adhesion molecule-1 is upregulated in spontaneously hypertensive rats: evidence for a prohypertensive role within the brain stem
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However, a placebo-controlled trial in 769 patients with MCI found that the same dosage of vitamin E did not affect the probability of progression from MCI to AD over a three-year period (108)
Thus, we have demonstrated that GSH-targeted therapy selectively kills PC cells in an oxidative stress-dependent manner and that the differences in basal ROS level and antioxidant scavenging capacity induced by stratified expression of VRK2 can well account for the heterogeneous sensitivity to GSH inhibition
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