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It's worth noting that tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist, representing a distinct but related medication class with similar clinical effects
Even tissues with relatively low GLP-1R expression, such as the liver and intestinal epithelium, can benefit indirectly through systemic metabolic improvements and paracrine signaling, as evidenced in conditions like NAFLD and inflammatory bowel disease (IBD) [56, 57]
Putting it all together: your personalized dosing decision After absorbing all of this information, here is how to synthesize it into a practical dosing plan for your specific situation
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