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1 Weight loss results Weight loss was a key secondary outcome: Semaglutide 0.5 mg: Weight loss of 4.3 kg Semaglutide 1.0 mg: Weight loss of 6.1 kg Sitagliptin 100 mg: Weight loss of 1.9 kg This means participants taking semaglutide 1.0 mg lost approximately 4.2 kg more than those taking sitagliptin over the same period
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Weight Loss Comparison Phase 3 Results Weight Loss Thresholds Retatrutide is the first obesity medication where over 50% of participants achieved 25% weight loss a threshold previously only reached with bariatric surgery
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