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Results: Cell necrosis and apoptosis were significantly induced by PA in a dose dependent manner
b) controlar los aspectos econmicos y financieros del consorcio
This PK-PD disconnect is compatible with a peptide whose mechanism triggers downstream signalling cascades (VEGFR2 activation, fibroblast migration, angiogenesis) that persist well beyond direct peptide presence
Ansorge, I., Benting, J., Bhakdi, S
All cells except for hNF-1 were grown and maintained as monolayer cultures at 37 C in 5% CO 2 in a humidified atmosphere, using DMEM (high glucose with l-glutamine and phenol red, Fujifilm Wako Pure chemical corporation), supplemented with penicillinstreptomycin solution (100) (Fujifilm Wako Pure Chemical Corporation), and 10 vol% FBS (Sigma-Aldrich Co., Llc.)
