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Neutrophils are required to pass through several barriers consisting of vascular endothelial cells, basement membranes, and pericytes to get to the site of infection or inflammation

Mumenthaler et al., 2008

systematically compared the transduction distribution of AAV1, 2, 5 and 8 serotypes in the knee joints of mice and found that different AAV serotypes showed different tissue tropisms in tissues such as synovium, cartilage and subsynovial bone (181)