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426 In contrast to AI/ML approaches that derive statistical correlations from data, mechanistic modeling builds mathematical representations based on underlying biological processes to explain and predict drug resistance
This study found that JMF4073 treatment suppresses the in vitro and in vivo growth of WT-Bcr-Abl-transformed leukemia cells, but T315I-Bcr-Abl-transformed cells are less susceptible
Gelbrich N, Miebach L, Berner J, Freund E, Saadati F, Schmidt A, Stope M, Zimmermann U, Burchardt M, Bekeschus S
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