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Dar HH, Epperly MW, Tyurin VA, Amoscato AA, Anthonymuthu TS, Souryavong AB, et al
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Essentially, upon activation, mTORC1 initiates the phosphorylation of eukaryotic initiation factor 4E binding protein 1 (4EBP1) and ribosomal protein S6 kinase 1 (Dong et al., 2018)
Where Phase I or Phase II human trials exist, they are noted in the compound page summary
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