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Preclinical studies in rodents have demonstrated reductions in fat mass, improved insulin sensitivity, and increased metabolic rate without significant changes to food intake (Neelakantan et al., 2019)
Citations Citations and reference data
Negative effects are rare but may include: Mild discomfort at the injection site, temporary diarrhea, allergic reactions, or rash
It is the most potent peptide for muscle growth but also carries more risk than the others in this section
Retatrutide (development code LY3437943) is a 39-amino acid synthetic peptide developed by Eli Lilly as the first triple-receptor agonist targeting GLP-1R, GIPR, and GCGR in a single molecule
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