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Lower doses (100-150 mcg) are typical for the first 2-4 weeks before titration
AMG 133 demonstrated significant dose-dependent weight loss in a phase 1 randomized, double-blind, placebo-controlled clinical trial involving participants with obesity, along with an acceptable safety and tolerability profile [124]
Ferrara G, Gianotti R, Cavicchini S, Salviato T, Zalaudek I, Argenziano G
Peptide-based approaches have been claimed to induce pigmentation changes that are more rapid and consistent than those reliant on external UV sources
I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals
