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In most other people, deficiency due to inadequate consumption of vitamin B12 is unlikely

In another investigation, a model was employed wherein gelatin methacryloyl hydrogel microchannels were either solely covered by HUVECs without fibroblasts (serving as the control), devoid of endothelial lining but containing encapsulated fibroblasts within the hydrogel, or with both endothelial lining along with encapsulated fibroblasts embedded within the matrix

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Proc Natl Acad Sci USA 2010

Its crucial to start with lower doses and monitor for any adverse reactions