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The molecular chaperone Hsp90 is required for meiotic progression of spermatocytes beyond pachytene in the mouse
It is recommended for two distinct indications: It is indicated in the treatment of vitamin B12 deficiency due to a lack of absorption - biermer's disease, - ablation of the stomach or part of the intestine, - imerslund's disease, and in this case it should be administered by intramuscular injection
Except for ASCT2 blockade, GPNA can also block SNAT1, SNAT2 and LAT1 (74)
NADPH is mainly derived from the pentose phosphate pathway, which uses glucose-6-phosphate dehydrogenase (G6PD) as the key enzyme [36]
doi: 10.2337/dc10-1006 253 SekharR
