Second generation: the synthetic Cytogens The synthetic peptides were designed as short sequences intended to represent the biologically active portion of the extracts
Copper peptides promote collagen and elastin production while ceramides ensure the skin barrier remains intact to retain these structural improvements
The DRI modification that stabilizes the peptide against degradation also means its elimination kinetics in humans are unknown
Some commonly used ones include: Oregano oil, thyme oil (carvacrol, thymol) Garlic/allicin / aged garlic extract Caprylic acid (from coconut oil) Pau dArco (Tabebuia impetiginosa) Berberine/goldenseal / Oregon grape root Berberine hybrids (e.g., berberine and catechins) Black walnut hull, wormwood, and garlic combinations Grapefruit seed extract Pomegranate / ellagic acid These botanicals may have antifungal, antibacterial, or antiparasitic properties and are often dosed in rotation (e.g., 2 weeks on, 1 week off) or reduced after a clearance phase
Commonly used in silico models include variations of Lipinskis rule of five, such as the CNS multiparameter optimization (MPO) score (c.f
