Its primary effects are mediated through three transcription factors from the GLI family, which includes GLI1, GLI2, and GLI3 (Omenetti et al., 2011
Punicalagin protects diabetic nephropathy by inhibiting pyroptosis based on TXNIP/NLRP3 pathway
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However, prolonged GC use poses risks such as glaucoma, cataracts, and infections, while Cyclosporine can cause a burning sensation