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SHMT2 has been reported to be highly expressed in pseudopalisading cells surrounding ischemic necrotic foci in GBM, suppressing PKM2 activity and limiting pyruvate entry into the TCA cycle [30]

DFP significantly increased 2-thiobarbituric acid reactive substances (TBARS) level in skeletal muscle in exercised NASH-HCC mice, but not in non-exercised NASH-HCC mice

Hajdink P, Czobor , Lrincz T, Szarka A (2019) The problem of glutathione determination: a comparative study on the measurement of glutathione from plant cells

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The next step, which researchers are actively pursuing, is to confirm this in a direct disc herniation model